SCIENTIFIC ACHIEVEMENTS OF THE TEACHING STAFF OF THE DEPARTMENT OF PHARMACEUTICAL AND TOXICOLOGICAL CHEMISTRY FOR THE 2025-2026 ACADEMIC YEAR

BoshkayevaA.K., d.pharm.s., Associate Professor, Chairman of the Scientific Committee of the School of Pharmacy, Head of the Department of Pharmaceutical and Toxicological Chemistry

Publication activity: has 8 articles in the Scopus database, H-index — 3, total number of citations-45. Editor-in-Chief of the proceedings of the XIV International Scientific and Practical Conference “Priorities of Pharmacy and Dentistry: from theory to Practice” (November 27, 2025). 2 teaching aids have been published (in Kazakh) and a methodological note is being prepared for publication:

1) Manual for practical training in Pharmaceutical Chemistry (June 2026). Author: A. K. Boshkayeva

2) Quantitative determination of Medicinal Products by service groups educational and methodological manual for students (June 2026). The Author: A.N. Seryakov, A.V. Voronin, V.A. Kataev, A.K. Boshkayeva, A.L. Akhelova.

3) Methodological recommendations “Safe disposal of medical resources” (June 26, 2026). Author: Boshkayeva A.K., Massakbayev A.J., Zhanabaykyzy S.

Research projects: participates in the EOM Competition for 2 grant projects, and also participated in the Competition of JSC “Science Foundation” with a project for commercialization.

2 grant projects:

1) “Pharmaceutical development of maral products (Cervus Elaphus Sibiricus), which has a therapeutic and preventive effect“.

2) “Pharmaceutical development and standardization of phytocomposite soft dosage forms with antiviral activity from medicinal plants of Kazakhstan”.

3 initiative projects have been registered with the National Center for Science and Technology Development:

1) Commercialization of an innovative technology for creating a therapeutic and preventive toothpaste based on vegetable raw materials (IRN DP25997469).

2) Commercialization of competitive cleaning products for therapeutic and preventive purposes for oral care (IRN DP32936272).

Inventive activity: in the last 5 years: 8 utility model patents, 1 invention patent, 1 international patent:

1.Authors: Akhmetova Gulmira Serikovna (KZ) Dyusenova Nurgul Zhetpisbayevna (KZ) Boshkayeva Asyl Kenesovna (KZ) Praliev Kaldybai Dzhaylovovich (KZ) Ilyin Alexander Ivanovich (KZ) Datkhaev Ubaydilla Makhambetovich (KZ) Dzhumagazieva Ardak Bisenbayevna (KZ) Iskakbayeva Zhanar Alibayevna (KZ) Seilkhanov Tulegen Muratovich (KZ)

Compound 1-methyl-4-(n-trifluoromethylл-)benzoyloxypiperidine hydrochloridewith antimicrobial and fungicidal activity

Joint-Stock Company “Institute of Chemical Sciences named after A. B. Bekturov”(KZ); Joint-Stock Company “Scientific Center of Anti-infectious Drugs” (KZ); Non-profit Joint-stock Company ” Kazakh National Medical University named after S. D. Asfendiyarov”(KZ).

№9481. Utility model patent, 17.06.2024

2.Бошкаева Асыл Кенесовна (KZ) Boshkayeva Assyl Kenesovna (KZ) (72) Масакбаев Абай Джолдасович (KZ) Қалибек Тоқжан Нұржанқызы (KZ) Наралы Назерке Ильясқызы (KZ) Таганов Жасур Ибрагимович (KZ). Utility model patent “Composition of an antibiotic-based filling toothpaste”. №8740, 17.05.2024

BoshkayevaAssylKenesovna (KZ) Massakbayev Abay Joldassovich (KZ) Aldasheva Maya Akhmetovna (KZ) Bolatbekova Akniet Eleuovna (KZ) Yussupov Rustam Rakhimovich (KZ) Fazylov Timur Rinatovich (KZ) Ibadullayeva Galia Saruarkyzy (KZ) Yunuskhodzhayeva Nodira Abdulhamitovna (UZ), No. 9520 Composition of temporary filling paste. Utility model patent, 24.02.2024

BoshkayevaAssylKenesovna (KZ), Masakbayev Abay Joldasovich (KZ), Kozhanova Kaldanay Karzhauovna (KZ), Oralbekova Madina Yerbolkyzy (KZ), Poroykov Vladimir Vasilyevich (RU), Yusupov Rustam Rakhimovich (KZ), Taganov Zhasur Ibragimovich (KZ), Fazylov Timur Rinatovich (KZ), Iskakova Maryam Kozbaevna (KZ). Utility model patent No. 9147 “Method for obtaining the enzyme cephalosporinase” dated 06.03.2024.

International patent WO 2023/282732 A1 of January 12, 2023 Composition of therapeutic and prophylactic toothpaste. Boshkayeva A.K., Massakbayev A.J. Telman M., Omarova R.A., Iskakova M.K.

Awards:

2025-2026 academic year:

Altynustaz (second degree), КазНМУS. D. AsfendiyarovKazNMUАсфендиярова

academic year:

Medaldedicated to the 135th anniversary of S. D. Asfendiyarov in honor знаменованияof the Independence Day of Kazakhstan (December 16, 2024).

2023-2024 academic year:

The title “Champion of KazNMU 2023”.

Certificate of a technology commercialization reactor participant.Astana, June 11, 2024

Leadership: 2024-2025 academic year

1) Tanaguzov T.M., 3rd year student majoring in Pharmacy

2) Zhuman Zhamilya Bolatkyzy, 3rd year student majoring in Pharmacy

3) Alimzhanova Kamila Armanovna 3rd year student majoring in Pharmacy

2023-2024 academic year:

1) Diyar Asel Batyrbekkyzy, 3rd year Pharmacy. Topic: “Creation of medicinal substances based on dihydroquercetin. Scientific supervisors: Boshkayeva A.K., Massakbayev A.J., 1st place in the 1st round of the Research and Development Institute of KazNMU named after S.D. Asfendiyarov. The scientific work won the Republican round (1st place).

2) Bolatbekova Akniet Eleuovna, 4th year of TFP. Topic: “Acquiring new filling masses for dental practice”. Scientific supervisors: Boshkayeva A.K., Massakbayev A.J. 3rd place in the 1st round of the Research and Development Institute of KazNMU named after S.D. Asfendiyarov. The scientific work won the Republican round (3rd place).

Ibragimova Z.E., specialist, head teacher of the Department of Pharmaceutical and Toxicological Chemistry

Publication activity and abstracts: has 1 article in the Scopus database, the H-index – 1. She is the co—author of a number of abstracts at the International Forum “ANaMed Forum – New Generation 2026” devoted to the phytochemical study of sage nutmeg and burdock.

Leadership: She is one of the scientific supervisors of the student team “VitaNova”, which took 2nd place at the International Subject Olympiad in” Pharmaceutical Chemistry “and” Pharmacognosy”.

Shukirbekova A. B., d.pharm.s., Professor, freelance part-time member of the Department of Pharmaceutical and Toxicological Chemistry

Publication activity: has 6 articles in the Scopus database, H-index — 3, total number of citations-58.

1) Sakipova Z., Wong Nikki Siu Hai, Bekezhanova T., Sadykova, Shukirbekova A., Boylan F. Quantification of santonin in eight species of Artemisia from Kazakhstan by means of HPLCUV: Method development and validation. PLoS ONE, 2017. DOI: 10.1371/journal.pone.0173714

2) Zhumashova G, Kukula-Koch W, Koch W,Baj T, SayakovaG, Shukirbekova A, Głowniak K, Sakipova Z. Phytochemical and Antioxidant Studies on a Rare Rheum cordatum Losinsk. Species from Kazakhstan. Oxidative Medicine and Cellular Longevity, 2019. DOI: 10.1155/2019/5465463

3)Zhumashova G., Kukula-Koch W., Koch W.,Baj T., Sayakova G., Shukirbekova A., Głowniak K., Sakipova Z. Erratum: Phytochemical and antioxidant studies on a rare rheum cordatum losinsk: species from Kazakhstan (Oxidative Medicine and Cellular Longevity (2019) 2019 (5465463) DOI: 10.1155/2019/5465463)

Oxidative Medicine and Cellular Longevity Erratum, 2020. DOI: 10.1155/2020/9692807

4) Sakipova Z., Giorno T.B.S., Bekezhanova T., Haiwong N.S., Shukirbekova A., Fernandes P.D., Boylan F. Pharmacological Evaluation of Artemisia cina Crude CO2 Subcritical Extract after the Removal of Santonin by Means of High Speed Countercurrent Chromatography. Molecules, 2020. DOI: 10.3390/molecules25122728

5)Narkevich I.A., Nemyatykh O.D., Medvedeva D.M., Akpaeva K.M., Sakipova Z.B., Shukirbekova A.B., Mironenkova Zh.V.Consumption of antiretroviral drugs in the Republic of Kazakhstan Medical Technologies. Assessment and Choice, 2022. DOI: 10.17116/medtech20224402122

6)Amrenova A., Shukirbekova A., Akhelova Sh., Assilbayeva J., Gurin A., Ualieva, M., Kaliyaskarova B., Sarsekeyev A., Mussin N.M. Tamadon A. Personalized PET Imaging in Gastric Cancer: An Umbrella Review of Meta-Analyses to Guide Radiopharmaceutical Selection and Clinical Indication. International Journal of Biomedical Imaging, 2026. DOI: 10.1155/ijbi/3450212

Kozhamzharova A.S., c.ch.s., Associate Professor of the Department of Pharmaceutical and Toxicological Chemistry

Publication activity: has 10 articles in the Scopus database, the H-index is 4, and the total number of citations is 30. Co-author of several scientific publications in international journals (Processes and PLoS ONE).

Inventive activity: Received 3 author’s certificates (in April 2026) for the development of technologies for the extraction of rosehip leaves, aloe vera and the creation of an ointment with calendula officinalis extract.

Leadership: Led student projects, including the project that won 2nd place in the competition “Artificial Intelligence (AI) Synergy in Education”.

Sharipova S.A., c.ch.s., Associate Professor without academic title of the Department of Pharmaceutical and Toxicological Chemistry

Publication activity: has 15 articles in the Scopus database, H-index-3, citation-18 (publications in the journals Molecules, Caspian Journal of Environmental Sciences and Journal of Nanostructures).

Awards: Awarded “Kurmet gramotasy” at the university level for her contribution to the development of the department.

Leadership: Acts as a research supervisor for students participating in cathedral research competitions and Olympiads in pharmaceutical chemistry.

Kaldybaeva A.K., c.ch.s.,Associate Professor without academic title of the Department of Pharmaceutical and Toxicological Chemistry

Publication activity: has 9 articles in the Scopus database, H-index-4, citation-25; one monograph presented at the III National Competition of publications “Global SciCall: Foundation for New Knowledge”.

Inventive activity: holds the author’s certificate for the development of the composition and technology of capsules with burdock extract (Arctium lappa).

Awards: certificate of merit of the trade union for active participation in the social and educational life of the university.

Leadership: SRWS Leadership.

Pushkarskaya N.S., Assistant of the Department of Pharmaceutical and Toxicological Chemistry

Publication activity

Has 3 articles in the Scopus database:

1)Afonin G., Ismaeel G., Al-Hussainy A.F., Hameed S.M., Abd B., Hussein L.A., Hamza H.H., Jalal S.S., Sharipova S., Massakbayev A., Pushkarskaya N., Ibragimova Z., Kaldybayeva A.,Enhanced Tumor Targeting: Curcumin-Loaded Chitosan Nanoparticles for Precision Drug Delivery: A Review. Journal of Nanostructures, 2024. DOI: 10.22052/JNS.2024.01.029

2) Mombekov S., Orazbekov Y., Sadykova N., Kozhamzharova A., Sharipova S., Makhatov Zh., Pushkarskaya N., DEVELOPMENT OF ANTIFUNGAL GEL, COMPOSITION AND TECHNOLOGY BASED ON POMIFERIN METABOLITE ISOLATED FROM FRUITS OF MACLURA AURANTIACA GROWING IN KAZAKHSTAN. ScienceRise: Pharmaceutical Science 2024. DOI: 10.15587/2519-4852.2024.299230

3)Boshkayeva A., Massakbayev A., Sayakova G., Mombekov S., Yussupov R., Arystanova T., Tazhiyeva A., Ibadullayeva G., Pushkarskaya N., Tleubayeva M., Aitzhanova G., Kayupova F., Kozhanova K. Exploring the frontiers of penicillin pharmaceuticals: a comprehensive review of advancements and innovations. Journal of Advanced Pharmacy Education and Research, 2026. DOI: 10.51847/2M8kLppG32

Индекс H-index — 1, citation-7.

Inventive activity:

Boshkayeva A.K., Kizatova M. Massakbayev A.J., Ibragimova Z.E., Pushkarskaya N.S., Diyar A.B., Akhanov E.B., Kastaeva Zh.B., Asaubaeva Zh. B., Development of the composition, technology of obtaining and evaluation of the quality of dental powder with therapeutic and preventive action / / Author’s certificate No. 66236 from 13.01.2026

Leadership:

The head of the student team “Analyst”, who participated in the International Subject Olympiad on “Pharmaceutical Chemistry” and “Pharmacognosy” and took 1st place.

The scientific supervisor is Feride Abdurakhimova, a 4th–year Pharmacy student who took 1st place in the International tournament “BIOPHARM QUIZ” and 2nd place in the video contest “Pharmacy Code – a bridge through time”.

The scientific supervisor is Nietullayeva Kamazhai, a 4th-year Pharmacy student who took 1st place in the Republican Chemistry Olympiad, organized by the “KKO.KZ” WEBSITE

8.Masakbayev A.J., Master’s degree, lecturer of the Department of Pharmaceutical and Toxicological Chemistry, responsible for SRW and SRWS of the Department

Publication activity: Author of 4 articles in the Scopus database, H-index-1, citation-2. Co-author of guidelines for the safe disposal of medicines.

Research projects: participation in the competition of JSC “Science Foundation”, commercialization of RNSTD. The project title is “Commercialization of an innovative technology for creating a therapeutic and preventive toothpaste based on vegetable rawmaterials”.

Inventive activity: copyright certificates, patents for utility models and inventions for the 2025-2026 academic year:

1.Ibadullayeva A.K., Kozhanova K. K., Boshkayeva А.К., Massakbayev A.J., Ibadullayeva G.S., Mukhamedsadykova A.Zh., Zhandabayeva M. A., Rysbay A.B. A method for obtaining an extract from plant raw materials of British elecampane (Inula britannica L.) / / Patent for utility model No. 10800 dated 20.03.2026

2.Boshkayeva А.К., Masakbaev A.J., Kizatova M.Zh., Ibadullayeva G.S., Kopbayeva M.T., Aidaralieva A. Composition of therapeutic and preventive dental powder // Utility Model patent No. 11859 dated 06.03.2026

3.Boshkayeva А.К., Masakbayev A.J., Sayyn O.K., Diyar A.B., Akhanov E.B., Omarova B.A., Dilmanov Zh.E., Jadranov E.S. The composition of therapeutic and prophylactic toothpaste // Utility model patent No. 11864 dated 03/06/2026

4.Tellman M. T., Boshkayeva A.K., Iskakova M.K., Berillo D.A., Massakbayev A.J. A sulfanilamide derivative with antibacterial and antifungal activity // Patent for inventions No. 37954 of 22.05.2026

5.Myrzakozha D.A., Karlova E.K., Aidaralieva A.B., Nechepurenko E.V., Aidaralieva A., Boshkayeva A.K., Masakbayev A.J. A method for stimulating hair growth using octadecyldimethylamine oxide (C18DAO) // Patent for utility model No. 12277 dated 22.05.2026

6.Boshkayeva A.K., Kizatova M.Zh., Massakbayev A.J., Ibragimova Z.E., Pushkarskaya N.S., Diyar A.B., Akhanov E.B., Kastaeva Zh.B., Asaubaeva Zh.B., Development of the composition, technology of obtaining and evaluation of the quality of dental powder with therapeutic and preventive action. No. 66236 of 13.01.2026

BoshkayevaAsylKenessovna, Massakbayev Abay Joldasovich, Zhanabaikyzy Saltanat. Safe disposal of medicines // Copyright certificate No. 71600 dated 05/04/2026

MassakbayevAbayJoldassovich, Boshkayeva Asyl Kenessovna, Poroikov Vladimir Vasilyevich, Kozhanova Kaldanai Karzhauovna, Sayakova Galiya Myrzagalievna, Ayupova Rizvangul Bagdauletovna. Creation of new pharmaceutical substances of the penicillin series // Copyright certificate No. 75350 dated 06/19/2026

Leadership: at the Department of Pharmaceutical and Toxicological Chemistry, head of the research and student circles “Pharmaceutical Analyst”, “Chemical Technologist”; head of student teams in the preparation of subject Olympiads: “VitaNova”, “Pharm vision”, “Pharm4ever” and “Veritas Pharm”.

Under his guidance, students received places:

– 3rd place at the International Scientific and Morphological Conference in Semey (Musanova Nargiz, Ubaydolla Aldiyar).

– 1st place in the International Student Olympiad in Pharmacy in honor of the 70th anniversary of Doctor of Pharmacy, Professor. Sagyndykova D.A. (Pharm vision team)

– 1st place in the All-Russian Olympiad for students in the discipline “Pharmaceutical Chemistry” (Alimzhanova Kamilla)

– 1st place in the All-Russian Olympiad for students in the discipline “Pharmaceutical Chemistry” (Kamila Mukhanova)

– 1st place in the All-Russian Olympiad for students in the discipline “Quality control of medicines” (Zhuman Zhamilya Bolatkyzy)

– 2nd place in the XII Republican subject Olympiad on the educational program 6B07201 – “Technology of pharmaceutical production” (Pharm4ever team)

– 2nd place in the International Subject Olympiad in “Pharmaceutical Chemistry” and “Pharmacognosy” (VitaNova Team)

– 1st place in the Intra-University Competition for Student Research (Diyar Asel)

– 3rd place in the Intra-University Competition for Student Research (Mahanbet Aruzhan, Serik Nurtaza)

Tolegenkyzy A., Master’s degree, PhD doctoral student of the 1st year of study in the specialty “Pharmaceutical production technology”, assistant of the Department of Pharmaceutical and Toxicological Chemistry, secretary of the SC School of Pharmacy

Teaching and research activities: assistant of the Department of Pharmaceutical and Toxicological Chemistry, PhD-doctoral student of the 1st year in the specialty “Pharmaceutical Production Technology”; Secretary of the Scientific Committee (SC) of the School of Pharmacy.

Leadership: co-head of SRWS.

Zhanabaykyzy S., Master’s degree, assistant of the Department of Pharmaceutical and Toxicological Chemistry

Pedagogical and scientific activity: Works as an assistant of the department, is a young scientist (up to 35 years old). He is a co-author of methodological guidelines and an author’s certificate on the safe disposal of medicines introduced into practical healthcare (at KazNMU and the Scientific Center for Anti-Infective Drugs).

Inventive activity: Co-author of a patent for a utility model for the production of a thick extract of wild rose.

Leadership: preparing students for the SRWS competition (scientific and research work of a teacher) and subject Olympiads. Under her leadership, research is underway on the synthesis of cephalosporin antibiotics and the development of ointment technologies.

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